It doesn't make much difference really. It's a question of what you're comfortable with for accommodations. Some areas are impossible for anything but a tent. These places are wonderful but I would suggest experiencing them while you are able to do it. When you get older, it doesn't mean you cannot still do it. But you reach a point when you just don't give a sh*t anymore and all you require is getting away. This is not to mention that going off into places that can only be reached on foot or horseback will leave a lot of places you've never experienced that can be reached using a Winnebago. Just get out there and do it.