To be really effective, you have to treat the whole environment.
Wash the dogs with a pyrethrin shampoo and let them dry, then use Frontline or some other spot treatment on the dogs.
Wash the bedding with hot water and detergent.
Use an indoor flea spray on the floor and all surfaces the dogs get on, like furniture.
I also treat the (fenced in) yard the dogs run in with wettable Sevin. (Sevin is very toxic to bees, so keep it off flowers.)
This routine always works for us- even in wet years when fleas are awful.
My $0.02, YMMV.
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